|
|
arachidonic_acid + O2 <=> 15-hydroperoxyeicosatetraenoic_acid
|
1.13.11.12
linoleate 13S-lipoxygenase
1.13.11.33
arachidonate 15-lipoxygenase
|
–
–
|
BMK
|
|
BRENDA:
BR47601
KEGG:
R01593
MetaCyc:
ARACHIDONATE-15-LIPOXYGENASE-RXN
SABIO-RK:
1742
|
|
|
|
15-hydroperoxyeicosatetraenoic_acid <=> 15-Oxo-5,8,11-cis-13-trans-eicosatetraenoate + H2O
|
4.2.1.152
hydroperoxy icosatetraenoate dehydratase
5.4.4.7
hydroperoxy icosatetraenoate isomerase
|
–
–
|
|
|
BRENDA:
BR51056
KEGG:
R10761
MetaCyc:
RXN-14946
|
|
|
|
15-hydroperoxyeicosatetraenoic_acid <=> a_hydroxyepoxyicosatrienoate
|
5.4.4.7
hydroperoxy icosatetraenoate isomerase
|
–
|
|
|
BRENDA:
BR51062
KEGG:
R10766
MetaCyc:
RXN-14947
|
|
|
|
2 glutathione + 15-hydroperoxyeicosatetraenoic_acid <=> GSSG + (15S)-hydroxyeicosatetraenoic_acid + H2O
|
1.11.1.9
glutathione peroxidase
|
–
|
K
|
|
KEGG:
R07035
|
|
|
|
15-hydroperoxyeicosatetraenoic_acid <=> 15H-11,12-EETA
|
1.14.14.1
unspecific monooxygenase
|
–
|
K
|
|
KEGG:
R07042
|
|
|
|
15-hydroperoxyeicosatetraenoic_acid <=> 11H-14,15-EETA
|
1.14.14.1
unspecific monooxygenase
|
–
|
K
|
|
KEGG:
R07043
|
|
|
|
15-hydroperoxyeicosatetraenoic_acid + reduced_acceptor <=> (15S)-hydroxyeicosatetraenoic_acid + H2O + acceptor
|
not assigned
|
–
|
M
|
|
MetaCyc:
RXN66-490
|
|
|
|
15-hydroperoxyeicosatetraenoic_acid + NAD+ <=> 15-Oxo-5,8,11-cis-13-trans-eicosatetraenoate + NADH
|
1.1.1.141
15-hydroxyprostaglandin dehydrogenase (NAD+)
|
–
|
|
|
BRENDA:
BS403306
|
|
|
|
15-hydroperoxyeicosatetraenoic_acid + glutathione <=> 15-hydroxyarachidonic_acid + GSSG
|
1.11.1.9
glutathione peroxidase
|
–
|
|
|
BRENDA:
BS261215
|
|
|
|
15-hydroperoxyeicosatetraenoic_acid + O2 <=> more
|
1.13.11.31
arachidonate 12-lipoxygenase
|
–
|
|
|
BRENDA:
BS260728
|
|
|
|
15-hydroperoxyeicosatetraenoic_acid + O2 <=> (8S,15S)-dihydroperoxy-(5Z,9E,11Z,13E)-eicosatetraenoic_acid + (5S,15S)-dihydroperoxyeicosatetraenoic_acid
|
1.13.11.12
linoleate 13S-lipoxygenase
|
–
|
|
|
BRENDA:
BS413672
|
|
|
|
15-hydroperoxyeicosatetraenoic_acid + O2 <=> (5S,15S)-dihydroperoxy-5,8,11-cis-13-trans-eicosatetraenoic_acid
|
1.13.11.34
arachidonate 5-lipoxygenase
|
–
|
|
|
BRENDA:
BS288907
|
|
|
|
2 arachidonic_acid + 2 O2 + H+ <=> 15-hydroperoxyeicosatetraenoic_acid + (15S)-hydroxyeicosatetraenoic_acid + H2O
|
1.13.11.33
arachidonate 15-lipoxygenase
|
–
|
|
|
BRENDA:
BS394704
|
|
|
|
arachidonic_acid + O2 <=> 15-hydroperoxyeicosatetraenoic_acid + (5Z,8Z,10E,14Z)-(12S)-12-hydroperoxyicosa-5,8,10,14-tetraenoate
|
1.13.11.33
arachidonate 15-lipoxygenase
|
–
|
|
|
BRENDA:
BS376302
|
|
|
|
15-hydroperoxyeicosatetraenoic_acid <=> (13R)-hydroxy-(14S,15S)-epoxyeicosa-(5Z,8Z,11Z)-trienoic_acid + (5Z,8Z,10E,14Z)-12-oxoicosa-5,8,10,14-tetraenoic_acid
|
4.2.1.152
hydroperoxy icosatetraenoate dehydratase
|
–
|
|
|
BRENDA:
BS429455
|
|
|
|
1-palmitoyl-2-arachidonoylphosphatidylcholine + O2 <=> 15-hydroperoxyeicosatetraenoic_acid
|
1.13.11.33
arachidonate 15-lipoxygenase
|
–
|
|
|
BRENDA:
BS440514
|
|
|
|
1-stearyl-2-arachidonyl_glycerol + O2 <=> 15-hydroperoxyeicosatetraenoic_acid
|
1.13.11.33
arachidonate 15-lipoxygenase
|
–
|
|
|
BRENDA:
BS440518
|
|
|
|
15-hydroperoxyeicosatetraenoic_acid <=> (13R)-hydroxy-(14S,15S)-epoxyeicosa-(5Z,8Z,11Z)-trienoic_acid
|
5.4.4.7
hydroperoxy icosatetraenoate isomerase
|
–
|
|
|
BRENDA:
BS429453
|
|
|
|
15-hydroperoxyeicosatetraenoic_acid <=> 13-hydroxy-14,15-epoxy-5,8,11-eicosatrienoic_acid + 15-ketoeicosatetraenoic_acid + 13-hydroxy-14,15-epoxy-5,8,11-eicosatrienoic_acid + 15-ketoeicosatetraenoic_acid
|
5.3.99.4
prostaglandin-I synthase
5.3.99.5
thromboxane-A synthase
|
–
–
|
|
|
BRENDA:
BS390566
|
|
|
|
15-hydroperoxyeicosatetraenoic_acid <=> (15S)-hydroxyeicosatetraenoic_acid + H2O
|
4.2.1.152
hydroperoxy icosatetraenoate dehydratase
|
–
|
|
|
BRENDA:
BS429081
|
|
|
|
15-hydroperoxyeicosatetraenoic_acid <=> (15S)-hydroxy-11,12-epoxyeicosatrienoic_acid + H2O
|
4.2.1.92
hydroperoxide dehydratase
|
–
|
|
|
BRENDA:
BS403006
|
|
|
|
2 guaiacol + 15-hydroperoxyeicosatetraenoic_acid <=> 15-hydroxyarachidonic_acid + H2O + 3,3''-Dimethoxydipheno-4,4''-quinone
|
1.14.99.1
prostaglandin-endoperoxide synthase
|
–
|
|
|
SABIO-RK:
11352
|
|